Yes. Some areas of the body are better than others at absorbing insulin. It depends on the consistency of fatty tissue in the area that you are injecting.
The abdomen has the best absorption. Many people use the abdomen for long-acting insulins and other areas, like the thighs, for short-acting or before-meal injections.
The back of the arm does absorb insulin well, but it's hard to maneuver the syringe to the correct spot (the fatty part at the back of the arm). It's also tough to inject in an area that you cannot see well. Plus, people tend to use the muscles of their arms more, and a lot of muscle motion can make insulin absorb too quickly.
When giving yourself an injection, the best way to make sure you're injecting into the fatty tissue is to firmly grasp the skin and tissue in the area with one hand, pinching it so that it is raised slightly, and inject the insulin into that area. Do not rub the area after the injection. Rubbing can also damage tissue.
Source:
"Insulin Injection Sites." Health Information. 04 APR 2004. University of Wisconsin Hospitals and Clinics Authority. 27 Sep 2007.
