Can Anti-Inflammatories Guard Against Type 2 Diabetes?
According to a January 28th press release from the American Diabetes Association (ADA), results from a study from Joslin Diabetes Centers showed that taking an anti-inflammatory drug called salsalate may help prevent type 2 diabetes
How does it work? Recent studies have shown that inflammation caused by excess fat cells, especially in the abdomen, bring about the metabolic changes that can lead to heart disease and diabetes.
The reasoning behind this study is to prove that if inflammation causes these damaging effects, then an anti-inflammatory medication might be helpful in preventing diabetes.
Salsalate did show a reduced instance of both glycemia and inflammation in obese test subjects.
For more information on ongoing studies that are testing the effects of salsalate and prevention of diabetes, click this link...
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Comments
It would certainly be more productive if they would find out what caused the inflammation instead of just prescribing another “drug” to suppress a symptom.
It is my understanding that the inflammation is caused in part by very high density very small lipoproteins - a form of cholesterol that is not measured in any current test. This teensy cholesterol gets in between the cell walls and causes the inflammation. And a way to prevent or reduce this from happening would be better than just leaving it there and stopping the cells from a “normal response to an irritant”. This teensy cholesterol is manufactured by our liver in response to high fasting levels of insulin - another test that is almost never done - even in diabetics who are obviously insulin resistant. It seems to me that the proper goal would be to help figure out how to reduce insulin resistance (using natural means if possible) which would then reduce the production of this teensy lipoprotein - and voila! Inflammation gone! PS. I saw a recent study in the Journal of Clinical Endocrinology and Metabolism - “Vanadyl Sulfate Improves Hepatic and Muscle Insulin Sensitivity in Type 2 Diabetes” 2001:86, pg 1410 by K. Cusi, et al. Vanadyl Sulfate - not a drug - a common mineral. This supplement also reduced A1C, plasma glucose levels, FBG’s - in general all the markers for diabetes. No effect on the normal control group. Oh, and for the readers out there, the currently available supplements are 7.5 mg and 10 mg. The amount used in this study was 150 mg per day and it takes four weeks to begin to show these effects.
The trouble with most of our “health” care is that it focuses on suppressing symptoms instead of finding the cause of the problem and addressing that first.
I really found this site to be very helpful and full of good information. Thank you for taking the time to post this info. I look forward to you writing again soon.
I am very interested in this research as I also have inflammatory bowel disease along with Type 2 diabetes. Anti-inflammatory medications used to treat IBD, such as predinose, however, tend to cause blood glucose to rise. I wonder if this new medication could treat both???